Enhance MD Reviews: What It Really Costs, Who It Fits, and the Catch

Enhance MD reviews praise the care and question the price. Enhance.MD offers cash-pay compounded (pharmacy-made) semaglutide or tirzepatide, not FDA-approved, with required labs and a live visit. Its four-week plans list $249 or $329 before first-order discounts. The advertised $112 first month is tied to a longer plan, not a confirmed checkout total.

The RX Index is the independent GLP-1 decision resource that scores telehealth providers and treatment paths on clinical legitimacy, care quality, transparency, access, and cost, so readers can choose the path that fits their situation.

The answer shifts if your state isn't on its published list, you want to use insurance or a health savings account (HSA) or flexible spending account (FSA) card, or you need an FDA-approved medicine. Below: the advertised plans, estimated upfront costs, and when paying ahead can save money.

RX Index Decision Verdict: A lab-first compounded program with a higher advertised starting price than some alternatives. Worth considering if your clinician identifies a need for compounded treatment and you value required bloodwork and a live visit; compare the full terms before paying.

• Best for: Cash payers in a state Enhance serves whose clinician identifies a need for compounded semaglutide or tirzepatide, and who want required labs, a live video visit, and a published price that doesn't increase by dose.
• Not ideal for: Anyone who needs FDA-approved medicine, insurance, or HSA/FSA card payment; anyone whose state Enhance cannot currently serve.
• The factor that matters most: Which plan you pick. Core's four-week price would be $199 if the advertised first-order offer applies; the 48-week option needs a much larger payment. Confirm that total before choosing.

A quick word on what this review is. We didn't sign up, pay, or receive medicine. We read Enhance's own price pages, FAQ, and terms, its public reviews, and the FDA documents that apply, all on October 23, 2026, and did the math so you don't have to. Where something can't be confirmed from the outside, we say so and give you the exact question to ask.

Already enrolled? Jump to cancellation and order help for official support details.

What does Enhance MD really cost?

Enhance lists $249 every 4 weeks for semaglutide (Core), $329 for tirzepatide (Advanced), and $379 for both together (Elite) on its pay-as-you-go plan. Medication, labs, visits, and shipping are included, per its FAQ. Longer plans advertise lower rates per four-week period and longer billing blocks; confirm the full payment before enrolling.

The $112 first month, explained

The homepage shows Core "starting at $112 first month" next to "$212/month." Both numbers belong to the plan Enhance calls 12-month.

Here's the math. The Core product page advertises 15% off $249 on the plan billed every 48 weeks. If that saving applies to each of 12 four-week periods and the $100 first-order offer is deducted once, the estimated initial charge is $2,439.80—about $2,440. That is our planning calculation, not a verified checkout total. Get the full charge in writing before paying.

Think of it like a gym that advertises "$10 your first month" on a contract that bills the whole year on day one. That advertised first-month rate doesn't tell you what leaves your account. The same question applies here: what is the full charge today?

Every plan's estimated first charge and renewal

All products below are compounded medicines, not FDA-approved. Listed rates are from Enhance's Core, Advanced, and Elite pages, checked October 23, 2026. For the payment estimates, we reduce the base four-week rate by the advertised percentage, multiply by the periods purchased, then deduct the first-order offer once. We round to the nearest dollar. These are calculations from the public offer, not checkout quotes; we couldn't verify the final total or limit how much it could differ.

Enhance's banner currently advertises "up to $150 off your first order." Its plan cards show $50 off the 1-month plan and $100 off longer plans. We didn't test promo codes at checkout, so the table uses the plan-card discounts.

One more thing that trips people up: 4 weeks isn't a month. Thirteen four-week periods cover 52 weeks—364 days. At the $249 base rate, that's $3,237 for the supply, or about $270 when spread across 12 budget months. That's a budgeting average, not a monthly bill.

What's included, and what isn't

Enhance's FAQ says the program price covers lab work, virtual visits with a provider, medication from its partner pharmacies, and shipping. Product pages add supplies (syringes and alcohol pads), coaching, and metabolic labs every 6 months. There's no separate membership fee.

Two details still matter:

• Your own pharmacy. If you ask Enhance to send the prescription to a pharmacy you choose, that pharmacy bills you for the medicine at its own price.
• Payment cards. Enhance's FAQ says it doesn't accept HSA/FSA cards, gift cards, or prepaid cards. Visa, Mastercard, Discover and American Express only.

Enhance also promises the "same price at every dose." It says a higher prescribed dose within the same plan doesn't carry a dose-based price increase. That's a useful policy to compare when you check the full offer.

Should you prepay or pay month to month?

Prepaying saves money only if you stay long enough to offset the larger payment. In this model, Core's 12-month plan is roughly tied with paying as you go at ten four-week periods, and saves meaningfully at eleven. The calculations below apply the advertised discounts and show payments before any refund. Enhance's public pages don't establish unused-term refund rights; its terms say full payment terms appear at checkout.

The three- and six-period break-even points also apply to Advanced and Elite. Their 12-period plans become cheaper at eleven periods; at ten, prepayment is about $16 more for Advanced and $26 more for Elite. If you use all 12 periods, the model saves about $642 on Advanced and $732 on Elite.

Say you're 45, starting your first GLP-1, and not sure how your stomach will handle it. It's worth asking what you would owe if you and your clinician decided to stop after three four-week periods. In this no-refund model, the 12-month plan costs about $1,743 more than paying as you go. If you've already stayed on a GLP-1 for most of a year, prepaying may be easier to budget for. If you haven't, paying as you go limits the amount committed at once. (See how long most people stay on GLP-1s and what happens when you stop.)

Watch the second charge, too. A 12-month plan lists billing every 48 weeks. If the first payment is day zero and that schedule holds, renewal falls on day 336—roughly a month before your one-year mark. Our Core renewal estimate is about $2,540, but confirm the actual amount and date. Put that date on your calendar the day you pay.

Check your own number

Pick a program and plan, then enter how many four-week periods you want to compare. The calculator estimates payments from the advertised offers, the prepaid time you might not use, and how that compares with paying as you go. It shows payments before any refund, not a checkout quote.

Worked example: Core, 12-month plan, compare 3 four-week periods. The model gives about $2,440 paid, with 9 prepaid periods unused. Paying as you go for those same 3 periods is $697 if the first $50 offer applies. That's about $1,743 less before any refund or extra charges.

The whole year on month to month

If you go month to month, here's the cost of the standard program over 52 weeks. Enhance's FAQ says medication through its partners, labs, visits and shipping are included. The table assumes those published inclusions apply; it isn't an audited checkout receipt.

These assume the $50 first-order discount applies once, prices don't change, and you don't pause. If the first payment is day zero and renewals stay exactly 28 days apart, a 14th charge falls on day 364: $3,436 paid for Core within days 0–364, with supply extending beyond that window. Your treatment may start after the first payment.

Not every reader needs the same thing from a GLP-1 provider. The right one depends on your goals, your state, your insurance and its formulary (the plan's list of covered drugs), whether you want an FDA-approved or compounded medicine, a shot or a pill, and your budget. Answer a few quick questions in The RX Index's Find My GLP-1 Path tool to see which GLP-1 paths and providers fit before you pay anyone. It's free, takes about 2 minutes, and needs no signup.

See which GLP-1 path fits you

If your clinician has identified a need for compounded treatment and price is the thing deciding this for you, it's fair to compare another program before you commit. On October 23, 2026, Embody advertised $69 a month for compounded semaglutide and $119 for compounded tirzepatide. Its terms tie those rates to 12-month bundles; the listed monthly-plan rates are $79 and $129. Confirm the total and renewal period for the plan you select.

The refund comparison matters, too. Enhance promises your full initial payment back if you're found ineligible during onboarding. Embody's refund policy generally makes payments final, but allows an unused-portion refund for provider-initiated medical disqualification, less services already provided. It requires cancellation at least 72 hours before renewal to stop the next charge. Read our Embody review for the full terms.

See Embody's current pricing

What do Enhance MD reviews say?

On Trustpilot, Enhance.MD has a 4.0 out of 5 TrustScore from 162 reviews (checked October 23, 2026). Happy reviewers praise easy scheduling, real conversations with clinicians, and fast replies. Unhappy ones point to price, upfront plans, delayed or canceled orders, warm deliveries, and a charge that wasn't refunded once the order was filled.

First, make sure it's the right Enhance

The GLP-1 program lives at enhance.md. Two unrelated businesses share the name: Enhance Medical Group, a UK cosmetic-surgery company, and Enhance MD Body Hair & Skin Clinic, a med spa in Inver Grove Heights, Minnesota. Their reviews say nothing about this program. The right Trustpilot profile is trustpilot.com/review/enhance.md.

What reviewers praise, and what they question

These are individual accounts, paraphrased from Trustpilot. We did not independently verify the events they describe, and none of them is evidence that a medicine is safe or works.

What the numbers say: 68% of all reviews are 5-star and 14% are 1-star. The profile lists 26 reviews in the last 12 months and replies to 25% of negative reviews. Enhance claimed the profile in January 2024, pays for a Trustpilot subscription, and invites customers to leave reviews.

The 20 review entries shown on the page when checked include ten 5-star, two 4-star, four 3-star and four 1-star reviews: a simple average of 3.7 (our math). That small, self-selected set isn't a service-failure rate, and its simple average is not the platform's 4.0 TrustScore. The negative accounts raise questions about orders, charges, shipping and support.

Where should you land? The praise gives you useful questions about care; it doesn't establish care quality. The money and logistics complaints give you practical checks: know your charge date, your cancel cutoff, and your pharmacy before you pay.

Is Enhance.MD legit? Who prescribes, and who fills it

Yes, Enhance.MD is a real business with named medical groups, published terms, a phone line, and a stated process. It's a technology platform: licensed clinicians at affiliated medical groups decide whether to prescribe, and outside compounding pharmacies make and ship the medicine. "Legit" doesn't mean FDA-approved; the weight-loss products reviewed here are compounded.

Quick facts

The pharmacy lists don't match

The published pharmacy lists differ. Enhance's FAQ names Tru Meds Rx, Strive Pharmacy, and Pharmacy Hub as its partner pharmacies. Its Terms of Service (effective August 28, 2025) name Rite-Away Pharmacy, Vios Compounding Pharmacy, and TruMedsRx. Enhance's product pages say its formulations are compounded under federal Section 503A, the rules for state-licensed pharmacies that make a medicine for an individual patient's prescription.

None of that tells you which pharmacy will fill your prescription. Ask for the pharmacy's name and address, then look it up with your state's board of pharmacy.

What Enhance says vs. what we could confirm

Is it available in your state?

Available (per Enhance's FAQ, October 23, 2026): Alaska, Arizona, California, Colorado, Connecticut, Delaware, District of Columbia, Florida, Idaho, Illinois, Indiana, Iowa, Kansas, Kentucky, Maine, Maryland, Massachusetts, Michigan, Minnesota, Montana, Nebraska, Nevada, New Hampshire, New Jersey, New Mexico, New York, North Carolina, Ohio, Oklahoma, Oregon, Pennsylvania, Rhode Island, South Dakota, Texas, Utah, Vermont, Virginia, Washington, West Virginia, Wisconsin, Wyoming.

Not listed: Alabama, Arkansas, Georgia, Hawaii, Louisiana, Mississippi, Missouri, North Dakota, South Carolina, Tennessee.

Some other reviews list West Virginia as unavailable; Enhance's own list includes it. Lists change, so confirm your state with Enhance before you pay.

Is compounded cheaper than FDA-approved medicine now?

At the starting prices shown below, the Wegovy pill plus Ro's first membership month costs less than Enhance Core's first four-week period. At the later doses shown, Enhance's published program price is lower than the Ro examples before insurance. That price comparison doesn't make the medicines interchangeable: Wegovy and Zepbound are FDA-approved; Enhance's medicines are compounded and are not.

Here's how the charges compare. Enhance says its standard price includes medication, labs, visits and shipping. Ro charges a membership plus medication and says it passes through the manufacturers' self-pay prices. All prices were checked October 23, 2026; the first-purchase examples assume the stated offers apply.

A few notes on that table. Ro lists the $199 Wegovy pen introduction for the first two eligible 28-day fills at 0.25 mg or 0.5 mg. NovoCare's terms limit it to patients who have not previously filled Wegovy injections through NovoCare or NovoCare Legacy: the prescription must be written and received by December 31, 2026, and shipped by January 31, 2027. The third fill uses the standard price. Ro lists Wegovy HD 7.2 mg at $399 per 28-day fill, so the $349 row is not the highest-dose price.

Zepbound's $449 price at 7.5 mg and higher depends on Lilly's self-pay offer. To keep it, the refill purchase must be completed within 45 days of receiving the previous supply. Ro tells patients to complete the refill check-in within that window; outside it, Ro lists $499 for 7.5 mg and $699 for 10–15 mg, before membership. The injection prices buy 28-day supplies; the pill price buys 30 days. Ro's membership follows its own monthly or prepaid term. These charges need not fall on the same date.

For budgeting, one ongoing fill plus one $149 membership month adds to $448 for the pill, $498 for the 2.4 mg pen, or $598 for Zepbound at the doses shown. After the first month, Ro also offers a 12-month membership at a $74 monthly equivalent—$888 prepaid for the term. Allocating $74 to one medicine fill gives $373, $423 or $523, respectively. Those are budget illustrations, not monthly invoices; medication is still billed separately. Confirm whether a separate multi-month medication offer changes your selected price.

If you already have your own doctor who'll prescribe, you can skip a separate telehealth membership, though your doctor's care may still cost money. Eligible cash-pay patients can get the Wegovy pill for $149 to $299 per 30-day fill through NovoCare Pharmacy, and Zepbound starts at $299 per 28-day supply through LillyDirect. See Wegovy pill cost without insurance and the cheapest ways to get Zepbound, or our side-by-side of compounded vs. brand-name GLP-1s.

So the honest trade in these cash-pay examples is this: Enhance has a lower published program price at the later doses shown, while the FDA-approved options have undergone FDA review for safety, effectiveness, and quality. Insurance, your own prescriber, or a different selected offer can change the cost comparison.

If you want FDA-approved medicine and ongoing telehealth support, Ro is the path we'd compare first. Its membership starts at $39, then is $149 month to month or a $74 monthly equivalent with the $888 annual plan prepaid; medication is billed separately. Review both charges before enrolling.

See Ro's FDA-approved options and prices

How Enhance MD works, from signup to first shipment

Enhance's published process runs: free intake, payment, lab work at Quest, a video visit once results arrive, then shipping if a clinician prescribes. Its FAQ places payment before the labs and visit. If the clinician finds you ineligible during onboarding, Enhance says it refunds your full first payment.

1. Free medical intake. Health history, goals, current medicines. Enhance says this step costs nothing.
2. Payment. The 1-month plan lists renewal every 4 weeks. Confirm the first renewal date, especially if labs or approval take longer.
3. Photo ID and a face photo. Required before you can receive care.
4. Labs at Quest Diagnostics. A comprehensive metabolic panel (CMP: liver, kidney, blood sugar and electrolytes), lipids (cholesterol and triglycerides), TSH (thyroid), and HbA1c (average blood sugar over about three months). Enhance recommends fasting first. Enhance says results generally reach it within about 1 to 2 business days after the lab visit, then appear in the portal.
5. Video visit. A clinician reviews your history and labs and decides whether to prescribe.
6. Shipping. Every order is reviewed by a provider before it ships. Two-day priority shipping is included, but Enhance's shipping policy (January 2025) says arrival isn't guaranteed.
7. Ongoing care. Core, Advanced and Elite list medication delivery every 4 weeks and labs every 6 months. Microdosing lists 12-week shipments; confirm its lab schedule. Ask how care-team messages, required visits and lab results affect refills.

Want to talk before you pay? Enhance's product pages have a "Book a Free Consultation" link. One reviewer valued getting a Zoom call before committing. Enhance doesn't say whether that call is with a clinician or its care team, so ask when you book.

Ask for the full lab list first. One reviewer reported an extra lab trip, followed by another request for a missing test. Ask for the complete list before you go. One trip is easier than two.

If your medicine arrives warm. Enhance's FAQ says its medication is designed to ship unrefrigerated and has been tested in extreme temperatures. The FDA recommends not using any injectable GLP-1 that arrives warm or with insufficient refrigeration. Go with the FDA: don't use it, and contact the pharmacy and your clinician about a replacement or another safe next step.

Is the medicine safe and legal?

Compounded semaglutide and tirzepatide are not FDA-approved, and the FDA doesn't review them for safety, effectiveness, or quality before they reach patients. They can still be legally prescribed for an individual patient under specific rules, but those rules have tightened since the brand-name shortages ended in 2024 and 2025. Enhance's own pages are upfront that its formulations are compounded and not FDA-approved.

What "compounded" means here

A compounded medicine is prepared for a patient's particular medical needs. Enhance says its products are made under rules requiring an individual prescription. It isn't an FDA-approved generic, and results from Wegovy or Zepbound trials don't establish the safety or effectiveness of Enhance's formulation. FDA says compounded drugs should be used only when an FDA-approved drug cannot meet the patient's medical needs.

Where the rules stand in 2026

• No shortage anymore. On its compounding policy page (update dated April 1, 2026), the FDA says semaglutide and tirzepatide are not on its drug shortage list or its list of bulk substances that large outsourcing facilities may use.
• One patient at a time. A pharmacy compounding under Section 503A must make the drug for an individual patient based on a prescription.
• No routine copies. The FDA says a compounded drug can count as "essentially a copy" of an approved one, and a prescriber can document a significant difference for an individual patient. Its own example: adding vitamin B12 to semaglutide doesn't automatically make it something different.
• Marketing is under watch. On March 3, 2026, the FDA sent warning letters to 30 telehealth companies over how they advertised compounded GLP-1s.

The FDA also says that, as of May 31, 2026, it had received 990 reports of adverse events associated with compounded semaglutide and more than 730 associated with compounded tirzepatide, and that reports are likely incomplete because many pharmacies aren't required to submit them. These are nationwide reports, not counts tied to Enhance, and do not establish that a medicine caused every event or show the chance of one happening.

What this means for you: supply can change, so know your exact dose in milligrams and your pharmacy's name. Ask what's in the vial besides the GLP-1, since one reviewer reported not tolerating added B12. For the full timeline, see is compounded GLP-1 still available? and our compounded GLP-1 enforcement tracker.

Is the Elite plan (semaglutide + tirzepatide) a good idea?

Ask hard questions before you choose it. The FDA labels for both Zepbound (revised August 2026) and Wegovy (revised June 2026) say using them with any other GLP-1 receptor agonist is not recommended. Those labels cover the brand-name products, not Enhance's blend; their combination warning is a specific reason to ask about the evidence for Elite.

A GLP-1 receptor agonist is a medicine that switches on the body's GLP-1 signal, which helps with fullness and blood sugar. Tirzepatide already works on two signals (GIP and GLP-1). Elite adds semaglutide on top, so you'd be taking two GLP-1 receptor agonists at once.

Enhance markets Elite for people who've plateaued and says it has the "potential for greater total weight loss." Its Elite page doesn't cite a study of the two medicines taken together. Before choosing it, ask your clinician: why two medicines instead of adjusting one, what evidence supports this exact blend, and how side effects will be watched. If you've stalled, our guide to the GLP-1 weight-loss plateau covers the other options.

Severe stomach pain that won't go away, repeated vomiting, or signs of dehydration need urgent medical care.

Microdosing: what 1 mg a week means

Enhance's Microdosing page lists tirzepatide at 1 mg a week and 12-week shipments. That's below the 2.5 mg starting dose on Zepbound's label; it doesn't establish an effective or safer dose for this compounded product. Enhance's homepage says weight loss "isn't the primary aim."

The priced options shown cover 12, 24 or 48 weeks; the four-week label had no price. Multiplying the displayed equivalents gives estimated totals of $567, $1,074 and $2,028, respectively. Those are planning calculations, not verified checkout totals. Compare it with other programs in our microdosing guide.

A 12-week shipment doesn't tell you how long an opened vial can be used. FDA advises discarding a multidose vial within 28 days after first use, even if the compounder's directions allow longer. Ask how many vials arrive and how that advice applies to the supplied product; don't assume one opened vial lasts the whole shipment interval.

When to talk with your own clinician first

Start with your own clinician before choosing a program if you're under 18, pregnant or planning a pregnancy, have type 1 diabetes, have a history of an eating disorder, or have a relevant medicine allergy or other complex medical history. The Wegovy and Zepbound labels list a personal or family history of medullary thyroid cancer (MTC, a rare thyroid cancer), or having multiple endocrine neoplasia type 2 (MEN 2, an inherited condition), as reasons not to take those drugs. They also list prior serious allergic reactions to the respective medicine or its ingredients. The other situations above call for individual assessment; they aren't all absolute label contraindications. See GLP-1 hard contraindications and GLP-1s, pregnancy, and birth control.

Can you cancel Enhance MD and get a refund?

Canceling and getting money back are two different things. Enhance says you can pause or cancel anytime by contacting support, and its terms say subscriptions renew unless canceled before the next billing cycle. The public refund promise we found covers your full initial payment if a clinician finds you ineligible during onboarding.

Already a member and need help with an order, a charge, or canceling? Email support@enhance.md or call 1-888-299-5088 (Mon–Fri 8am–8pm ET, Sat–Sun 9am–5pm ET), or use the official Enhance.MD sign-in. Ask for written confirmation of your cancellation and your next billing date. If an order is stuck, ask whether it's waiting on a visit, a lab, the prescription, the pharmacy, or the carrier.

The timing matters. One reviewer said Enhance wouldn't refund a charge once the order had been filled, even though they emailed within minutes. Ask support to confirm both your next billing date and the last point when that prescription order can be canceled. Don't wait until it is already being processed.

Questions to send before you prepay

Copy these into an email to support@enhance.md and save the reply:

Before I pay, please confirm in writing: (1) the exact medicine I'd receive and every other ingredient in it; (2) the pharmacy's name and address; (3) the full amount charged today, the next charge amount, and its date; (4) how many weeks each payment covers; (5) whether anything (labs, visits, supplies, shipping) could be billed separately; (6) when billing starts if my labs or approval are delayed; (7) what happens to unused prepaid weeks if I stop, I'm found ineligible later, I move to a state you don't serve, or the medicine becomes unavailable; and (8) the cutoff for canceling before a refill is sent to the pharmacy.

Who should choose Enhance MD, and who should skip it

Consider Enhance if your clinician identifies a need for compounded medicine, you want required labs and a live visit, and Enhance confirms it serves your state. Choose another path if you need FDA-approved medicine, insurance, or an HSA/FSA card at checkout. If price leads your decision, compare the full bill and exit terms before committing.

Enhance's program is cash-pay. If using eligible insurance matters most, compare Ro's insurance-support program or your own prescriber. With cash-pay care, there's no insurer prior authorization—a permission slip—to wait on, but medical review, prescribing and pharmacy processing still come first.

Where to go instead:

• Want to compare lower advertised compounded prices: read our Embody review.
• Want a pill, not a shot: Enhance doesn't offer one. See Wegovy pill cost without insurance.
• Have Medicare: Enhance can't bill it. See the Medicare GLP-1 Bridge.
• Have Medicaid: see GLP-1 providers that accept Medicaid.
• Want to use HSA/FSA money: Enhance won't take the card. Whether you can be reimbursed later is a separate question; see are compounded GLP-1s HSA/FSA eligible?
• Not sure about your BMI: Enhance lists a minimum of 25 for new patients, or 20 for maintenance patients currently taking or recently treated with a GLP-1. BMI is a height-to-weight screening measure. For adult weight management, the Wegovy and Zepbound labels cover obesity, or overweight with a weight-related condition; the cited adult weight-management trials enrolled people with BMI 30 or more, or 27 to 29.9 with a condition. These are separate from Enhance's intake rules, and a clinician decides whether a medicine fits. Check yours on our GLP-1 BMI eligibility chart.

If you have insurance through work, Enhance can't use it, but it may cover an FDA-approved option. Ro offers a free coverage check for Wegovy, Zepbound and Ozempic pens. That check provides information; it doesn't request treatment or write a prescription. If you join its paid program and a clinician prescribes, its insurance team can handle prior-authorization paperwork for supported plans. Coverage is not guaranteed, and insurance does not pay the membership fee. If you have Medicaid, start with your plan and clinician; Ro currently excludes Medicaid patients from treatment.

Check your coverage with Ro

What we actually verified

Checked October 23, 2026:

• Enhance.MD's homepage, FAQ, How It Works page, all four GLP-1 product pages, Shipping & Returns policy (dated January 2025), and Terms of Service (effective August 28, 2025).
• Enhance.MD's Trustpilot profile, the 20 review entries displayed on its first page, and the older Christine Raymond review on page two.
• The FDA labels for Zepbound (revised August 2026) and Wegovy (revised June 2026); the FDA's pages on compounded GLP-1 policy (update dated April 1, 2026) and unapproved GLP-1 concerns; and the FDA's March 3, 2026 warning-letter announcement.
• Ro's pricing, insurance and free-checker pages; NovoCare's self-pay terms; Lilly's self-pay pricing and offer terms; and Embody's homepage, terms and refund policy.

Provider-stated, not independently verified: patient counts, weight-loss stories, the medical director's name, "same price at every dose," and what's included in each plan.

Our math: prepaid estimates and break-even points use the base price and advertised percentage discounts, not a verified checkout quote. The 52-week supply and 365-day payment examples use the assumptions stated beside them.

What we couldn't confirm: the exact checkout total on prepaid plans; whether unused prepaid weeks are refunded; which pharmacy fills a given order; and who runs the free consultation call. A targeted search of FDA warning-letter pages didn't turn up a letter addressed to Enhance.MD. That isn't proof of safety, and searches can miss things.

What we didn't do: enroll, complete an intake, pay, test cancellation, receive medicine, or inspect a pharmacy.

We haven't published a numeric score for Enhance.MD; this review uses our Decision Verdict. See how we evaluate providers.

Enhance MD reviews FAQ

Is Enhance MD legit?

Yes. Enhance.MD is a real cash-pay telehealth platform with named medical groups, required labs, and a live video visit before prescribing. Its weight-loss medicines are compounded and not FDA-approved, so "legit" is about the business, not FDA approval.

How much does Enhance MD cost?

The four-week base prices are $249 for semaglutide, $329 for tirzepatide, and $379 for the combination; the product cards advertise $50 off the first order. Longer plans show lower equivalents and larger billing blocks. Our percentage-based estimate for Core's 48-week first payment is about $2,440, but its actual checkout total was not verified.

Is the $112 first month real?

The homepage advertises it, but it is not a verified one-period purchase for $112. It pairs the offer with $212, the displayed equivalent on the 48-week plan; $112 is that displayed rate less $100. Confirm the full block charge and how the promotion applies before paying.

Are there extra fees?

Enhance's FAQ says its price includes labs, visits, medication from its partner pharmacies, and shipping, with no separate membership fee. If you choose your own pharmacy, that pharmacy bills you for the medicine. Ask whether anything else applies to your plan before paying.

Which pharmacy does Enhance MD use?

Its FAQ names Tru Meds Rx, Strive Pharmacy, and Pharmacy Hub. Its Terms of Service name Rite-Away Pharmacy, Vios Compounding Pharmacy, and TruMedsRx. Ask for the name and address of the pharmacy filling your prescription and check its license with your state's board of pharmacy.

How long until my first shipment?

It depends on how fast you get labs done, when results arrive (Enhance says generally about 1 to 2 business days after the lab visit), and when you book your video visit. Once a clinician prescribes and the order is reviewed, Enhance ships with 2-day priority, though its policy says arrival isn't guaranteed.

Does Enhance MD take insurance?

No. Its terms say services are cash-pay and can't be billed to Medicare, Medicaid, or other government programs. If you want to use insurance, look at an FDA-approved option through your plan.

What states is Enhance MD available in?

40 states plus D.C., per its FAQ on October 23, 2026. It isn't listed in Alabama, Arkansas, Georgia, Hawaii, Louisiana, Mississippi, Missouri, North Dakota, South Carolina, or Tennessee.

Is there an Enhance MD coupon or promo code?

Enhance's site banner advertises "up to $150 off your first order." Its plan cards show $50 off the 1-month plan and $100 off longer plans. We didn't test codes at checkout, so confirm the discount before you pay.

Does Enhance MD have complaints?

Yes. On Trustpilot, 14% of its 162 reviews are 1-star. Recent complaints focus on delayed or canceled orders, warm deliveries, a dose label error, and a charge that wasn't refunded once filled. Praise focuses on clinicians, scheduling, and quick replies.

Do I need lab work?

Yes. Enhance requires labs at Quest Diagnostics before prescribing: a metabolic panel, lipids, TSH, and HbA1c. Core, Advanced and Elite list repeat labs every 6 months, and the FAQ says labs are included. Confirm the schedule if you're considering Microdosing.

Can I use my HSA or FSA card?

Not at checkout. Enhance's FAQ says it doesn't accept HSA or FSA cards. Whether you can submit receipts for reimbursement is a separate question for your plan administrator.

How do I cancel Enhance MD?

Email support@enhance.md or call 1-888-299-5088, and get written confirmation. Ask for your next billing date and the cutoff for stopping a prescription order, then cancel before both. Enhance's public pages don't say whether unused prepaid weeks are refunded, so ask before you prepay.

Is the Elite plan stronger than Advanced?

It's different, not proven stronger. Elite combines compounded semaglutide and tirzepatide, and the FDA labels for Wegovy and Zepbound say using either with another GLP-1 receptor agonist isn't recommended. Ask your clinician what evidence supports the blend for you.

Is Enhance MD the same as Enhance Medical Group or the Minnesota med spa?

No. Enhance.MD (enhance.md) is an online GLP-1 program. Enhance Medical Group is a UK cosmetic-surgery business, and Enhance MD Body Hair & Skin Clinic is a med spa in Minnesota.

Before you pay, make sure you know the medicine, the pharmacy, the full charge, the renewal date, and the refund rules.

Sources

All checked October 23, 2026. Policy and label dates are listed where the source shows them.

• Enhance.MD — Homepage
• Enhance.MD — GLP-1 Core (semaglutide)
• Enhance.MD — GLP-1 Advanced (tirzepatide)
• Enhance.MD — GLP-1 Elite (semaglutide + tirzepatide)
• Enhance.MD — Microdosing Tirzepatide
• Enhance.MD — FAQ
• Enhance.MD — How It Works
• Enhance.MD — Shipping & Returns (policy dated January 2025)
• Enhance.MD — Terms of Service (effective August 28, 2025)
• Trustpilot — Enhance.MD reviews
• FDA — FDA's concerns with unapproved GLP-1 drugs used for weight loss (checked October 23, 2026)
• FDA — FDA clarifies policies for compounders as national GLP-1 supply begins to stabilize (update dated April 1, 2026)
• FDA — FDA warns 30 telehealth companies against illegal marketing of compounded GLP-1s (March 3, 2026)
• Eli Lilly — Zepbound prescribing information (revised August 2026)
• Novo Nordisk — Wegovy prescribing information (revised June 2026)
• Ro — Weight loss pricing
• NovoCare — Wegovy self-pay pharmacy terms
• Eli Lilly — Zepbound KwikPen self-pay pricing statement
• Embody — Homepage
• Trustpilot — Additional Enhance.MD reviews, page two
• Trustpilot — Enhance Medical Group, the separate UK business
• EnhanceMD Body Hair & Skin Clinic — Minnesota practice
• Ro — Insurance program and free coverage checker
• Eli Lilly — Current Zepbound self-pay offer terms
• Ro — Zepbound product and refill-offer details
• Embody — Terms and Conditions (dated April 24, 2026)
• Embody — Cancellation and Refund Policy (dated August 25, 2026)